Table 1.

Comparison of previously-reported ED₅₀ values and doses of agonists used.

Drug	previous ED50 (mg/kg)	current dose (mg/kg)	~ratio
CP55940	0.14, 0.05 1	0.3, 1	3, 10
THC	0.85, 0.78 4	10	12
methanandamide	20, 24 2	50, 250	2.3, 11
O-1812	0.014, 0.050 3	2.5	78
JWH-073	0.42, 1.1 4	20	26

The “previous ED₅₀” values are those reported for the latency to tail withdrawal test and hypothermia in mice, respectively, though some were converted from other units (e.g. μmol/kg) to mg/kg. “Current dose” is that used in the present study and the “~ratio” is the current dose divided by the average of the previous ED₅₀ values.

¹(Fan et al. 1994)

²(Adams et al. 1995)

³(Di Marzo et al. 2001)

⁴(Wiley et al. 1998)