Figure 4.

Plasticity of recurrent intra-amygdala network. (A) High-frequency stimulation (HFS) of thalamic afferents produces long-term potentiation (LTP) of the monosynaptic field potential response recorded in the superior part of the LAd, a potentiation that lasted at least 90 min. At the same time, long-term depression (LTD) of the intra-LA network was observed. This was evidenced by a depression of the monosynaptic field potential evoked in the superior part of LAd (LAd-s) in response to the stimulation of the inferior part of the LAd (LAd-i) (B); This was also observed as a general decrease in the amplitude of polysynaptic peaks (filled red dots), representing LTD in the network activity (C).