TABLE 2.

Baseline characteristics of the Women’s Health Initiative Coronary Artery Calcium Study stratified by oophorectomy status

		Bilateral oophorectomy					Unilateral or partial oophorectomy					No oophorectomy
		Previous HT use: ever					Previous HT use: ever					Previous HT use: ever
		Yes		No			Yes		No			Yes		No
Continuous variables	Units	No.	Mean	No.	Mean	Pa	No.	Mean	No.	Mean	Pa	No.	Mean	No.	Mean	Pa	Pb
Age at WHI enrollment	y	272	55.4	106	55.7	0.56	77	55.3	99	54.4	0.09	192	55.48	267	54.6	<0.01	0.04
Body mass index	kg/m2	271	30.5	105	31.8	0.05	76	31.1	99	31.7	0.58	190	29.90	267	30.1	0.79	0.03
Cigarette smoking	Pack-years	262	9.2	103	13.1	0.06	76	9.8	96	9.55	0.89	186	9.00	262	10.9	0.26	0.94
Physical activity	MET-h/wk	245	10.0	97	8.7	0.40	67	12.3	79	7.2	0.07	166	11.02	228	10.3	0.55	0.14
Time since hysterectomy	y	270	13.5	106	15.9	<0.01	77	18.2	99	15.7	0.01	191	16.66	267	16.6	0.95	<0.01
Time since oophorectomy	y	269	12.9	103	14.9	0.02	77	18.6	98	15.8	<0.01	–	–	–	–	–	<0.01
Categorical variables	Group	No.	%	No.	%	Pa	No.	%	No.	%	Pa	No.	%	No.	%	Pa	Pb
Randomization (CEE)	CEE	135	49.6	46	43.4	0.28	40	52.0	49	49.5	0.75	104	54.2	136	50.9	0.49	0.23
Hypertension	Yes	97	38.0	42	42.4	0.45	37	53.6	42	48.3	0.51	62	36.1	91	37.8	0.72	0.03
High cholesterol	Yes	16	6.7	11	12.1	0.11	11	16.4	9	11.1	0.35	22	13.3	24	10.5	0.39	0.32
Diabetes	Yes	9	3.3	8	7.55	0.08	5	6.5	9	9.09	0.53	4	2.1	14	5.24	0.16	0.11
Hot flashes or night sweats	Yes	174	63.9	39	37.1	<0.01	55	71.4	56	57.1	0.05	138	73.4	141	53.6	<0.01	0.09

HT, hormone therapy; WHI, Women’s Health Initiative; CEE, conjugated equine estrogens.

^aP value for comparison of HT use to no HT use within each oophorectomy status.

^bP value for comparison between oophorectomy groups.