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. Author manuscript; available in PMC: 2009 Sep 24.
Published in final edited form as: ACS Nano. 2008 May;2(5):889–896. doi: 10.1021/nn800072t

Figure 10.

Figure 10

Fluorescence microscopy images showing the effect of folic acid modification on the NPs (green fluorescence). The cell nuclei were stained with DAPI (blue fluorescence), and the membranes were stained with WGA (red fluorescence). Top figures: HFF treated with (a) NPs and (b) folate-modified NPs. Bottom figures: PANC-1 treated with (c) NPs and (d) folate-modified NPs. Increased uptake of the folate-modified NPs was observed with the PANC-1 cells (overexpressed folate receptor) but not with the HFF.