Table 2.
Correlation between the clinicopathological features and expression of Cripto-1
| Cripto-1 | ||||
|---|---|---|---|---|
| Clinicopathological variables |
Cases (n = 37) |
positive (%) | negative (%) | p value |
| n = 20 | n = 17 | |||
| Gender | 0.627 | |||
| Male | 26 | 14 (53.8) | 12 (46.2) | |
| Female | 11 | 6 (54.5) | 5 (45.5) | |
| Age(years)a | 0.540 | |||
| ≤ 49 | 21 | 11(52.4) | 10 (47. 6) | |
| >49 | 16 | 9 (56.3) | 7 (43.7) | |
| Pathological classification(WHO) | 0.062 | |||
| Type I-II | 17 | 12(70.6) | 5 (29.4) | |
| Type III | 20 | 8 (40.0) | 12 (60.0) | |
|
Depth of invasion T classification |
0.474 | |||
| T1-2 | 27 | 14(51.9) | 13 (48.1) | |
| T3-4 | 10 | 6(60) | 4(40) | |
|
Lymph node metastasis N classification |
0.034c | |||
| N0 | 9 | 2 (22.2) | 7 (77.8) | |
| N1-3 | 28 | 18(64.3) | 10 (35.7) | |
| Distant metastasis | 0.036c | |||
| Yes | 5 | 5(100.0) | 0(0.0) | |
| No | 32 | 15 (48.4) | 17(51.6) | |
| Clinical Stagingb | 0.007c | |||
| I-II | 15 | 4 (26.7) | 11 (73.3) | |
| III-IV | 22 | 16(72.7) | 6(27.3) | |
agrouping of age was performed according to median.
bclinical staging was performed according to 1992 Fuzhou NPC staging system of China.
c statistical significance (p < 0.05)