Table 3.
Association between antibiotic resistance and pherotype.
| Antibiotic | CSP-1 | CSP-2 | OR (95% CI)a | FDRb | ||
|---|---|---|---|---|---|---|
| Resistant | Susceptible | Resistant | Susceptible | |||
| Penicillinc, d | 92 | 249 | 21 | 121 | 2.13 (1.24;3.78) | 0.012 |
| Erythromycin | 32 | 309 | 16 | 126 | 0.82 (0.42;1.65) | 0.611 |
| Clindamycin | 22 | 319 | 16 | 126 | 0.54 (0.26;1.15) | 0.141 |
| Tetracyclined | 18 | 323 | 20 | 122 | 0.31 (0.16;0.70) | 0.010 |
| Chloramphenicold | 5 | 336 | 9 | 133 | 0.22 (0.05;0.75) | 0.013 |
| Co-trimoxazoled | 89 | 252 | 17 | 125 | 2.59 (1.45;4.86) | 0.005 |
| Cefuroximed | 68 | 272 | 12 | 129 | 2.68 (1.38;5.64) | 0.010 |
a Odds ratio (OR) measures the strength of the association between a pherotype and resistance to a particular antibiotic. In each case, if OR is significantly > 1, CSP-1 is associated with resistance to that antibiotic and if OR is significantly < 1 this means that CSP-2 is associated with resistance to that particular antibiotic.
b Correction for multiple testing performed by the false discovery rate method (FDR)
c p < 0.05 after FDR correction.
d Both penicillin intermediate and fully resistant isolates were considered resistant for this analysis.