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Sequence features associated with strand selection in human and fly miRNAs
| Human | Fly | |||
| All annotated miRNA and new microRNA* | First nuclotide | U (36%) | U (51%) | |
| Purine or Pyrimidine bias | No | No | ||
| Strand-biased miRNA | Selected strand | First nucleotide | U (79%) | U (80%) |
| Purine bias | Yes | No | ||
| Excluded strand | First nucleotide | C (76%) | C (37%) G (27%) | |
| Pyrimidine bias | Yes | No | ||
| GC basepair | 25/33 (76%) | 15/30 (50%) | ||
