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. 2009 Oct 6;4(10):e7290. doi: 10.1371/journal.pone.0007290

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Terrados et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Increased chromosomal instability in W438 hPolλ-expressing cells. Metaphase spreads of either untreated (UT) or 2 Gy-treated (IR) cells corresponding to either control clones (DRA10 and CT2B), or to clones overexpressing either R438 (R1, R2) or the W438 variant (W1, W2) of hPolλ. (B) Examples of chromosomal aberrations observed in cells expressing the W438 variant of hPolλ.