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. Author manuscript; available in PMC: 2009 Sep 25.
Published in final edited form as: Clin Cancer Res. 2005 Jul 15;11(14):5206–5214. doi: 10.1158/1078-0432.CCR-05-0091

Figure 3.

Figure 3

Estimated survival distribution functions of time to local failure for a “typical” dog in the low and high thermal dose groups from the Cox proportional hazards model. There is a significant association between thermal dose group and time to local failure after controlling for total duration of heating, tumor volume and tumor grade (hazard ratio of low vs. high=2.28 (95% CI: 1.12–4.64); p-value=0.023). Duration of heating and tumor volume values used in the estimation of survival fuctions were median values for the respective group and overall, respectively. Htmin=total duration of heat treatment; median duration of heating in the thermal dose group was used in the plot. Stumvol=median tumor volume over all dogs in trial.