The Plant Mediator Complex Is a Key Regulator of JA-Dependent Plant Defense and Flowering Time.
The Arabidopsis Mediator subunit PFT1, possibly by acting downstream from a COI1-JAZ-MYC2 complex, integrates JA-dependent defense and developmental (e.g., phytochrome) cues by coordinating information from DNA-bound activators. This enables the RNA polymerase II complex to initiate the transcription of genes involved in flowering time and JA-dependent pathogen defense. GTFs, general transcription factors.
[See online article for color version of this figure.]