Figure 5.

miR-200 family and EMT marker levels in a panel of non-small-cell lung cancer cell lines. (A) Heat map of expression patterns for miRNAs in the miR-200 family and markers of EMT in a panel of 40 human lung cancer cell lines. Correlation of each gene or miR expression with that of miR-141 is indicated by Pearson's R- and P-values to the right. (B) Volcano plot showing the log-transformed P-values plotted against the log-transformed fold change in expression between cell lines derived from primary tumors relative to those derived from metastatic sites. miRs in red are differentially expressed more than twofold, with P < 0.05. (C) Table with x- and P-values corresponding to the highlighted miRs in B.