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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: FEBS J. 2009 Feb;276(4):995–1006. doi: 10.1111/j.1742-4658.2008.06836.x

Figure 5. Aβ levels in tg-ArcSwe mice without plaque pathology and their relation to spatial learning.

Figure 5

Aβ protofibril levels in TBS-extracts and total Aβ levels in formic acid extracted brains of 4 months old tg-ArcSwe mice were investigated and related to spatial learning (n=9). (A) Aβ protofibrils inversely correlated with improvement in escape latency, measured as performance in the last trial subtracted from performance at the first acquisition session. (B) Levels of total Aβ, in the same set of mice, were not associated with improved escape latency and spatial learning.