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. Author manuscript; available in PMC: 2009 Sep 25.
Published in final edited form as: J Immunol. 2006 Sep 1;177(5):3028–3034. doi: 10.4049/jimmunol.177.5.3028

FIGURE 3.

FIGURE 3

Renal disease is ameliorated in gld.apoE−/− mice after simvastatin treatment. The wt (n = 5), apoE−/− (n = 7), gld (n = 9), and gld.apoE−/− (n = 11) mice were treated with simvastatin (+) or vehicle control (−) for 12 wk. A, Proteinuria was measured in a 24-h urine collection. B, Representative H&E-stained sections of kidney. Glomerulus size in the gld.apoE−/− mice is shown with arrows. C, Glomerular tuft size was measured by computer-assisted pixel counting (*, p < 0.001). Values shown are the mean ± SD.