Table 1.
Echocardiographic Baseline and Sacrifice Parameters of Sheep with Stretched Leaflets
| Baseline | Sacrifice | p | |
|---|---|---|---|
| LVEDV (ml) | 58±13 | 62±13 | 0.32 |
| LVESV (ml) | 25±9 | 31±8 | 0.14 |
| LVEF % | 57±6 | 54±6 | 0.07 |
| MV leaflet area (cm2) | 14.3±1.9 | 16.7±1.9 | 0.006 |
| Leaflet length A2 (mm) | 17.4±1.3 | 19.4±1.5 | 0.02 |
| Leaflet length P2 (mm) | 14.6±1.9 | 15.9±1.7 | 0.02 |
| Annular area (diastole, cm2) | 8.35±1.57 | 9.64±1.38 | 0.03 |
| Annulus AP diameter (cm) | 2.7±0.4 | 3.2±0.2 | 0.06 |
| Annulus CC diameter (cm) | 3.8±0.4 | 3.8±0.5 | 1 |
| Tenting volume (cm3) | 1.67±0.59 | 3.26±0.91 | 0.02 |
| Vena contracta (cm) | 0.07±0.12 | 0.12±0.19 | 0.6 |
Student's paired t-test, two-sided
A2: anterior MV leaflet, middle scallop; AP: anteroposterior; CC: commissure-to-commissure; LVEDV: left ventricular enddiastolic volume; LVESV: left ventricular endsystolic volume; LVEF: left ventricular ejection fraction; MV: mitral valve; P2: posterior MV leaflet, middle scallop;