Figure 4. T5Cyp potently restricts lentiviruses that encode CA with CypA-binding activity.
(A–E) CRFK cells stably expressing the indicated TRIM5 proteins were transduced with increasing amounts of single-cycle GFP vectors derived from HIV-1NL4-3 (A), HIV-2ROD (B), SIVAGMtan (C), FIVPET (D), or SIVMAC251 (E). The percentage of GFP+ cells was determined 48 hours later.