Figure 4. T5Cyp potently restricts lentiviruses that encode CA with CypA-binding activity.

(A–E) CRFK cells stably expressing the indicated TRIM5 proteins were transduced with increasing amounts of single-cycle GFP vectors derived from HIV-1_NL4-3 (A), HIV-2_ROD (B), SIV_AGMtan (C), FIV_PET (D), or SIV_MAC251 (E). The percentage of GFP⁺ cells was determined 48 hours later.