Locomotor function was analyzed using BMS (A) and subscore (B) analyses. The main BMS score reveals general quadrupedal locomotor ability, while the subscore reveals differences in fine locomotor control (e.g., stepping frequencies, percentage forelimb–hind limb coordination, ability to execute stepping without medial or lateral paw rotation, relative trunk stability and tail position). n = 16–17/group from 2 replicate studies giving equivalent results. *P < 0.05, **P < 0.01, versus WT; 2-way ANOVA with repeated measures, Bonferroni post-test.