Figure 2. Family Pedigrees of 11 Patients with Childhood-Onset Idiopathic Cardiac Hypertrophy and No Family History of Cardiomyopathy.
Mutations identified in patients (arrows) were studied in family members, and their clinical status was ascertained. The plus symbol denotes the presence of the mutation, the minus symbol the absence of the mutation, and NA mutation status not available. Four mutations that were not detected in parents were new, and seven mutations were inherited from one parent. Circles denote female family members, squares male family members, solid symbols clinically affected family members, open symbols clinically unaffected members, and blue symbols family members with unknown clinical status.