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. 2009 Oct 13;6(10):e1000163. doi: 10.1371/journal.pmed.1000163

Table 5. Model-estimated mean change in CD4 cell count and weight after initiation of ART, by baseline WHO stage (n = 404).

Measures of clinical and Biological Status Between 0 to 6 mo Mean (95% CI) Between 6 to 24 mo Mean (95% CI)
Weight change (kg)
WHO Stage I 1.8 (0.6–3.0) 0.5 (−3.8 to 4.7)
WHO Stage II 1.8 (1.0–2.6) 1.0 (−1.3 to 3.3)
WHO Stage III/IV 4.4 (3.5–5.2) 1.8 (−0.2 to 3.7)
CD4 cell count (cells/µl)
WHO Stage I 96.7 (69.4–124.1) 126.0 (−9.6 to 261.5)
WHO Stage II 94.0 (76.1–111.7) 79.1 (14.2–144.0)
WHO Stage III/IV 128.0 (108.7–147.3) 128.9 (65.0–192.7)

Models also control for site, age, gender, and ART regimen (AZT-containing and/or NVP-containing). CD4 model also controls for baseline weight, dichotomized at the gender-specific median. Excludes 30 patients who either died or were transferred prior to the 6-mo visit/measurement.