Table 5. Model-estimated mean change in CD4 cell count and weight after initiation of ART, by baseline WHO stage (n = 404).
Measures of clinical and Biological Status | Between 0 to 6 mo Mean (95% CI) | Between 6 to 24 mo Mean (95% CI) |
Weight change (kg) | ||
WHO Stage I | 1.8 (0.6–3.0) | 0.5 (−3.8 to 4.7) |
WHO Stage II | 1.8 (1.0–2.6) | 1.0 (−1.3 to 3.3) |
WHO Stage III/IV | 4.4 (3.5–5.2) | 1.8 (−0.2 to 3.7) |
CD4 cell count (cells/µl) | ||
WHO Stage I | 96.7 (69.4–124.1) | 126.0 (−9.6 to 261.5) |
WHO Stage II | 94.0 (76.1–111.7) | 79.1 (14.2–144.0) |
WHO Stage III/IV | 128.0 (108.7–147.3) | 128.9 (65.0–192.7) |
Models also control for site, age, gender, and ART regimen (AZT-containing and/or NVP-containing). CD4 model also controls for baseline weight, dichotomized at the gender-specific median. Excludes 30 patients who either died or were transferred prior to the 6-mo visit/measurement.