Fig. 1.
Effects of acute endotoxemia on TREM mRNA expression. Macrophages and endothelial cells were isolated from livers of control C3H/OuJ (white bars) or TLR-4 mutant C3H/HeJ (black bars) mice 3–48 hr after administration of LPS or control (CTL). TREM mRNA was quantified by real time PCR. Data are presented as fold change relative to CTL. Each bar is the mean ± SD (n=12) from 3–4 separate experiments. *Significantly different (p<0.05) from CTL.