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. 2009 Sep 15;101(Suppl 1):S23–S26. doi: 10.1038/sj.bjc.6605273

Table 2. Rates of FN associated with the use of adjuvant FEC-T chemotherapy in high-risk node-positive patients with early breast cancer: a UK perspective (Head et al, 2008).

Data audited Patients audited Audit findings Recommendation Plan to re-audit
FN rate 137 25% Primary G-CSF should be used throughout treatment with FEC-T Following introduction of primary prophylaxis with G-CSF
Dose delays   25/137 (18.2%)    
Dose reductions   27/137 (19.7%)    
Use of primary G-CSF   30 patients    
FN rate after primary G-CSF   2/30 (8.5%)    
Use of secondary G-CSF   25%    
FN rate after secondary G-CSF   0