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. Author manuscript; available in PMC: 2010 Jul 15.
Published in final edited form as: J Immunol. 2009 Jun 24;183(2):945–952. doi: 10.4049/jimmunol.0900921

Figure 8. Peripheral blood CD4+HLA-DR+ T cells express less CLIP than CD19+ B cells.

Figure 8

(A) Cell surface expression of CLIP and intracellular expression of HLA-DM in peripheral blood mononuclear cells purified from a representative donor, gated on CD3+CD4+HLA-DR+ T cells or CD19+HLA-DR+ B cells (CD3 gate shown for CD4+ cells; MFI indicated; isotype control shown in grey). (B) CLIP mean fluorescence intensity (MFI; **p=0.001; mean±SEM; n=3), (C) relative frequency of CLIP+ cells (expressed as %CLIP+/%HLA-DR+; **p=0.002; mean±SEM; n=5) in CD3+CD4+ T cells or CD19+ B cells ex vivo and (D) the ratio of CLIP to HLA-DR in CD3+CD4+HLA-DR+ T cells versus CD19+B cells (expressed as [CLIP (MFI)/HLA-DR (MFI)]*100; **p=0.0047; mean±SD).