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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Bioorg Med Chem Lett. 2008 Oct 31;19(1):222–225. doi: 10.1016/j.bmcl.2008.10.107

Table 3.

Summary of in vitro data for trichloro- and trifluorophenyl derivatives.

graphic file with name nihms88185f9.jpg
Compound R1 R2 R3 R4 RNH2 IC50 (μM)
9v CI CI CI H NH2CH2CH2OH 0.005
9w F H F F NH2CH2CH2OH 0.134
9x F H F H NH2CH2CH2OH 0.035