Table 2.
Markers | Allele frequencies | Association tests | ||||||
---|---|---|---|---|---|---|---|---|
No. | rs_id | Celera ID | Minor allele | nVMR (103) | ARa(110) | TDT p-value | nVMR vs. ARap-value | |
1 | rs1376681 | C___3005257_10 | C | 0.475 | 0.458 | 0.5127 | 0.7182 | |
2 | rs1430397 | C___8798299_10 | T | 0.328 | 0.453 | 0.5637 | 0.0094 | |
3 | rs1505204 | C___3187363_10 | C | 0.475 | 0.388 | 0.5775 | 0.0720 | |
4 | rs1389464 | C___2021191_10 | C | 0.471 | 0.432 | 0.1573 | 0.4329 | |
5 | rs1433897 | C___8461299_10 | A | 0.387 | 0.402 | 0.2888 | 0.7600 | |
6 | rs1378736 | C___8797974_10 | G | 0.460 | 0.486 | 0.6547 | 0.5947 | |
7 | rs2499949 | C__16029966_10 | A | 0.221 | 0.201 | 0.7630 | 0.6222 | |
8 | rs916111 | C___9599131_1_ | A | 0.431 | 0.458 | 0.6949 | 0.5848 | |
9 | rs951748 | C___1451737_10 | C | 0.475 | 0.481 | 0.8527 | 0.9053 | |
10 | rs934460 | C___1451536_10 | C | 0.475 | 0.500 | 0.8415 | 0.6111 | |
11 | rs1498553 | C___1452175_10 | C | 0.461 | 0.453 | 0.0679 | 0.8707 | |
12 | rs1453424 | C___7695347_10 | C | 0.279 | 0.338 | 0.2207 | 0.1965 | |
13 | rs1377512 | C___9604514_10 | G | 0.279 | 0.349 | 0.2207 | 0.1263 | |
14 | rs1463289 | C___9604619_10 | C | 0.421 | 0.386 | 0.7237 | 0.4680 | |
15 | rs17480 | C__12033057_10 | G | 0.446 | 0.411 | 0.0164 | 0.4715 | |
16 | rs1462983 | C___9604662_10 | T | 0.396 | 0.401 | 0.2393 | 0.9189 | |
17 | rs649358 | C___8904618_10 | A | 0.453 | 0.424 | 0.0043 | 0.5617 | |
18 | rs399208 | C___3109726_10 | A | 0.485 | 0.495 | 0.0196 | 0.8363 | |
19 | rs984371 | C___3109488_10 | C | 0.201 | 0.217 | 0.2008 | 0.6883 | |
20 | rs1384101 | C____268897_10 | C | 0.119 | 0.179 | 0.5271 | 0.0850 | |
21 | rs2460211 | C___8132897_10 | A | 0.325 | 0.386 | 0.8575 | 0.1994 | |
22 | rs1481928 | C___1870209_10 | C | 0.328 | 0.387 | 0.8575 | 0.2146 | |
23 | rs1945245 | C__11666818_10 | T | 0.267 | 0.307 | 0.4328 | 0.3774 | |
24 | rs637404 | C____746124_10 | C | 0.307 | 0.316 | 0.3532 | 0.8415 | |
25 | rs502943 | C____732012_10 | T | 0.381 | 0.429 | 1.0000 | 0.3196 | |
26 | rs1788998 | C___8905573_10 | C | 0.387 | 0.420 | 0.8474 | 0.4987 | |
27 | rs1793426 | C___8905725_10 | A | 0.307 | 0.362 | 0.8415 | 0.2372 | |
28 | rs501828 | C___3043337_10 | G | 0.431 | 0.395 | 0.0499 | 0.4553 | |
29 | rs1943482 | C___7986115_10 | G | 0.299 | 0.302 | 0.1936 | 0.9492 | |
30 | rs3781902 | C___8131596_10 | A | 0.500 | 0.533 | 0.3692 | 0.5005 | |
31 | rs2848634 | C___2950363_10 | G | 0.196 | 0.278 | 0.5127 | 0.0490 | |
32 | rs1783826 | C___2864618_10 | T | 0.371 | 0.495 | 1.0000 | 0.0114 | |
33 | rs530094 | C____924939_1_ | A | 0.275 | 0.215 | 0.2253 | 0.1565 | |
34 | rs1704781 | C___1983937_10 | C | 0.289 | 0.238 | 0.3173 | 0.2375 | |
35 | rs921134 | C___2161631_10 | G | 0.319 | 0.330 | 0.2008 | 0.8012 | |
36 | rs2245676 | C___1334145_10 | G | 0.480 | 0.297 | 0.8273 | 0.0001 | |
37 | rs1938663 | C__11388708_10 | G | 0.392 | 0.373 | 0.0719 | 0.6822 | |
38 | rs2515366 | C__10094781_10 | T | 0.436 | 0.429 | 0.0143 | 0.8850 | |
39 | rs1938596 | C___3185821_10 | G | 0.436 | 0.435 | 0.0143 | 0.9721 | |
40 | rs1938709 | C___8137912_10 | A | 0.230 | 0.250 | 0.8185 | 0.6399 | |
41 | rs1892866 | C__11330707_10 | T | 0.500 | 0.552 | 0.7055 | 0.2893 | |
42 | rs1938781 | C___3160372_10 | G | 0.255 | 0.298 | 0.4913 | 0.3274 | |
43 | rs1545527 | C___8141059_10 | C | 0.319 | 0.294 | 0.8273 | 0.5910 | |
44 | rs3758872 | C__11668147_10 | C | 0.000 | 0.000 | 0.0578 | n.a. |
TDT, transmission disequilibrium test; SNPs, single-nucleotide polymorphisms; nVMR, nonallergic vasomotor rhinitis.
AR, allergic rhinitis; these patients do not have nVMR.