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Representative brain coronal sections of a COG1410-treated MCAO animal and an MCAO-only animal (A). B: Cerebral infarct analysis was determined at 12 areas per section and displayed a rather uniform pattern of cell survival within each treatment group. Infarct volume analysis showed that treatment with COG1410 reduced infarct volume by 10% vs. vehicle-treated animals (*P < 0.05). Data are plotted as mean ± SEM percentage of infarct volume from volume of undamaged hemisphere.
