Table 3. The prevalence, extent and intensity of inflammation in the foreskins of HIV-infected and HIV-uninfected men.

	Epithelium					Stromaa
	HIV+N=97		HIV-N=135			HIV+N=97		HIV-N=135
Extent of inflammationb	n	%	n	%	Pc	n	%	n	%	P
Any inflammationd	28	28.9	8	5.9	<0.001	53	54.6	29	21.5	<0.001
Focal	28	28.9	8	5.9	<0.001	40	41.2	29	21.5	0.001
Moderately diffuse	0	-	0	-	-	13	13.4	0	-	N/A
Intensity of inflammatione
Moderate	9	9.3	7	5.2	0.22	19	19.6	3	2.2	<0.001
Prominent	0	-	0	-	-	3	3.1	0	-	N/A

^aDefined as the subepithelial connective tissue compartment.

^bDistribution of inflammatory infiltrate throughout the tissue.

^cAs determined by Fisher exact test.

^dPrevalence of inflammation within the foreskin at time of circumcision by tissue compartment and HIV status.

^eRelative density of inflammatory infiltrate.