Table 2.
Number of genes expressed differentially* within a functional category by the BALF-exposed malT mutant
| Functional category | Up-regulated genes | Down-regulated genes |
|---|---|---|
| Protein biosynthesis | 2 | 7 |
| Amino acid biosynthesis | 6 | 2 |
| Cofactor biosynthesis | 4 | 8 |
| Biofilm formation | 4 | 0 |
| Nucleotide biosynthesis | 3 | 0 |
| Lipid biosynthesis | 0 | 2 |
| Lipid degradation | 1 | 0 |
| Cell envelope biosynthesis | 3 | 10 |
| Cellular processes | 5 | 2 |
| Central intermediary metabolism | 0 | 4 |
| DNA metabolism | 3 | 6 |
| Energy metabolism | 7 | 18 |
| Protein folding and stabilization | 2 | 2 |
| Regulatory proteins | 7 | 2 |
| Transcriptional regulators | 0 | 5 |
| Secretion and trafficking | 4 | 10 |
| Mobile and extra-chromosomal function | 2 | 0 |
| Unclassified and unknowns | 51 | 41 |
| Total | 104 | 119 |
* Differential expression of a gene in the malT mutant is relative to the level of expression of the gene in the wild-type organism, as measured in microarray experiments.