Table 2.
Sensitivity, 1-Specificity, and c Index of Clinical Signs and Symptoms and ADA Definition (N=64)
| Sensitivity (TPF) | 1 – Specificity (FPF) | c(AUC) | P-value* | Specificity (1 – FPF) | |
|---|---|---|---|---|---|
| Classical signs of infection: | |||||
| Increasing pain | .12 | .00 | .56 | .055 | 1.00 |
| Erythema | .32 | .23 | .55 | .31 | .77 |
| Edema | .20 | .23 | .48 | >.5 | .77 |
| Heat | .12 | .15 | .48 | >.5 | .85 |
| Purulent exudate | .26 | .35 | .47 | >.5 | .65 |
| Signs specific to secondary wounds: | |||||
| Serous exudate | .88 | .79 | .54 | .30 | .21 |
| Sanguinous exudate | .83 | .91 | .46 | >.5 | .9 |
| Delayed healing | .48 | .46 | .51 | .54 | .54 |
| Discolored granulation | .28 | .15 | .56 | .18 | .85 |
| Friable granulation | .00 | .23 | .38 | >.5 | .77 |
| Pocketing | .04 | .08 | .48 | >.5 | .92 |
| Foul odor | .20 | .13 | .54 | .33 | .87 |
| Wound breakdown | .00 | .03 | .49 | >.5 | .97 |
| ADA definition†: | .52 | .54 | .49 | >.5 | .46 |
*
The p-value is for testing the one-side alternative hypothesis that a “yes” response is more indicative of high microbial load patients.
†
Purulent exudate and/or two signs of inflammation