Table 2.
Comparison of the number of significant peptides by FDR in the Salmonella data (left) and simulation data (right)
Salmonella typhi |
Simulation |
|||||
---|---|---|---|---|---|---|
FDR | 0.01 | 0.05 | 0.10 | 0.01 | 0.05 | 0.10 |
Raw | 266 | 399 | 473 | 0 | 58 | 77 |
EigenMS | 444 | 476 | 476 | 80 | 82 | 87 |
Global | 211 | 312 | 372 | 96 | 150 | 172 |
Smoothing | 245 | 345 | 412 | 200 | 200 | 200 |
ANOVA | 462 | 476 | 476 | 60 | 79 | 80 |
In the simulation, there were 200 peptides, of which only 80 were differentially expressed.