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. Author manuscript; available in PMC: 2009 Sep 27.
Published in final edited form as: Epilepsia. 2007 Jul 25;48(11):2023–2046. doi: 10.1111/j.1528-1167.2007.01189.x

Table 2.

Summary of animals included in viral vector-mediated gene transfer study.

Total Number of Mice Numbers of Mice with Infection Rating
good poor none
Wildtype:
  
  
  
  
    lacZ alone
 8
 1
(4 mo / 4 dpi)
 2
(3 mo/ 4 dpi)
 5
(3.1 mo / 6dpi)
    lacZ+Kcna1
 5
 3
(4 mo / 6.5 dpi)
 2
(3 mo / 6 dpi)
 0
Kv1.1−/−:
  
  
  
  
    lacZ alone
 8
 3
(4.5 mo / 3.7 dpi)
 2
(3 mo / 5 dpi )
 3
(3.3 mo / 6 dpi)
    lacZ + kcna1 14 4
(4.8 mo /3.8 dpi)		 5
(3.8 mo /4 dpi)		 5
(2.1 mo / 6 dpi)

Vector efficacy was scored semi-quantitatively, based on the frequency and localization of β-gal-labeled hippocampal neurons, as follows: good - infection of many neurons in dentate gyrus and CA3 subfield; poor - sporadic labeling of single cells in dentate gyrus or CA3 subfield; none - no labeling of any neurons. Numbers in parenthesis indicate average age in months (mo) at time of vector infection, and average days post-infection (dpi) at the time of sacrifice and brain fixation (e.g., 3mo/4dpi).