Table 3.
African Americans |
Non-Hispanic whites |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Quartiles of MR-proANP (pmol/L) | Quartiles of MR-proANP (pmol/L) | |||||||||
I | II | III | IV | I | II | III | IV | |||
<44 | 44–62 | 62–93 | >93 | P trend | <44 | 44–63 | 63–95 | >95 | P trend | |
Age- and sex-adjusted | ||||||||||
SBP, mm Hg | 136.8±1.2 | 140.5±1.3 | 142.2±1.2 | 146.9±1.5 | <.0001 | 131.7±1.1 | 136.0±1.0 | 136.1±1.1 | 136.4±1.3 | 0.0098 |
0.026 | 0.0007 | <.0001 | 0.002 | 0.005 | 0.012 | |||||
Pulse pressure, mm Hg | 56.8±0.9 | 60.0±1.0 | 61.4±1.0 | 65.2±1.2 | <.0001 | 56.8±0.9 | 60.6±0.8 | 60.5±0.9 | 63.4±1.1 | 0.0002 |
0.011 | 0.0004 | <.0001 | 0.0009 | 0.003 | <.0001 | |||||
Hypertension severity score | 2.31±0.07 | 2.38±0.07 | 2.37±0.07 | 2.84±0.08 | <.0001 | 1.91±0.05 | 2.05±0.06 | 2.10±0.07 | 2.21±0.07 | 0.016 |
0.47 | 0.57 | <.0001 | 0.11 | 0.034 | 0.002 | |||||
Adjusted for age, sex, conventional risk factors and medication use | ||||||||||
SBP, mm Hg | 137.3±1.2 | 140.8±1.2 | 141.7±1.2 | 147.8±1.5 | <.0001 | 131.8±1.1 | 135.7±0.9 | 136.0±1.2 | 136.8±1.3 | 0.013 |
0.027 | 0.006 | <.0001 | 0.003 | 0.010 | 0.006 | |||||
Pulse pressure, mm Hg | 57.0±1.0 | 60.4±0.9 | 61.3±1.0 | 66.0±1.2 | <.0001 | 57.0±0.09 | 60.5±0.08 | 60.4±1.0 | 63.2±1.1 | 0.0006 |
0.006 | 0.001 | <.0001 | 0.002 | 0.009 | <.0001 | |||||
Hypertension severity score | 2.36±0.07 | 2.42±0.07 | 2.41±0.07 | 2.78±0.08 | 0.0013 | 1.92±0.05 | 2.05±0.06 | 2.11±0.07 | 2.18±0.07 | 0.028 |
0.51 | 0.60 | 0.0002 | 0.086 | 0.025 | 0.005 |
SBP, systolic blood pressure; MR-proANP, midregional pro-atrial natriuretic peptide.