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. Author manuscript; available in PMC: 2009 Sep 27.
Published in final edited form as: Am J Hypertens. 2009 Feb 12;22(4):425–431. doi: 10.1038/ajh.2009.8

Table 3.

Mean±SE SBP, pulse pressure, and hypertension severity in quartiles of plasma MR-proANP levels

African Americans
Non-Hispanic whites
Quartiles of MR-proANP (pmol/L) Quartiles of MR-proANP (pmol/L)

I II III IV I II III IV
<44 44–62 62–93 >93 P trend <44 44–63 63–95 >95 P trend
Age- and sex-adjusted
SBP, mm Hg 136.8±1.2 140.5±1.3 142.2±1.2 146.9±1.5 <.0001 131.7±1.1 136.0±1.0 136.1±1.1 136.4±1.3 0.0098
0.026 0.0007 <.0001 0.002 0.005 0.012
Pulse pressure, mm Hg 56.8±0.9 60.0±1.0 61.4±1.0 65.2±1.2 <.0001 56.8±0.9 60.6±0.8 60.5±0.9 63.4±1.1 0.0002
0.011 0.0004 <.0001 0.0009 0.003 <.0001
Hypertension severity score 2.31±0.07 2.38±0.07 2.37±0.07 2.84±0.08 <.0001 1.91±0.05 2.05±0.06 2.10±0.07 2.21±0.07 0.016
0.47 0.57 <.0001 0.11 0.034 0.002

Adjusted for age, sex, conventional risk factors and medication use
SBP, mm Hg 137.3±1.2 140.8±1.2 141.7±1.2 147.8±1.5 <.0001 131.8±1.1 135.7±0.9 136.0±1.2 136.8±1.3 0.013
0.027 0.006 <.0001 0.003 0.010 0.006
Pulse pressure, mm Hg 57.0±1.0 60.4±0.9 61.3±1.0 66.0±1.2 <.0001 57.0±0.09 60.5±0.08 60.4±1.0 63.2±1.1 0.0006
0.006 0.001 <.0001 0.002 0.009 <.0001
Hypertension severity score 2.36±0.07 2.42±0.07 2.41±0.07 2.78±0.08 0.0013 1.92±0.05 2.05±0.06 2.11±0.07 2.18±0.07 0.028
0.51 0.60 0.0002 0.086 0.025 0.005

SBP, systolic blood pressure; MR-proANP, midregional pro-atrial natriuretic peptide.