Table 2.
Mean pre- and post-cardiopulmonary bypass (CPB) values for patients separated by ventricular septal defect shunt direction. There was no significant difference between the right-to-left (R-L) and left-to-right (L-R) shunting groups in these parameters at baseline. P-values are for the difference in the pre- to post- change between the two groups. (PRSW=Preload Recruitable Stroke Work, LV SA=Left Ventricular Stroke Area, LV SW=Left Ventricular Stroke Work, LV EFa=Left Ventricular Ejection Fraction, LVEDA=Left Ventricular End-Diastolic Area, Am=EDA corrected Myocardial Area).
| R-L (n=6) |
L-R (n=5) |
||
|---|---|---|---|
| PRSW (mmHg) |
Pre-CPB | 36.0±3.6 | 32.9±3.6 |
| Post-CPB | 21.8±3.7 | 21.9±5.0 | |
| Change, p=0.68 | -14.2±4.5 | -11.0±6.1 | |
| LV SA (cm2/m2) |
Pre-CPB | 5.0±0.8 | 8.6±1.5 |
| Post-CPB | 4.2±0.6 | 4.0±0.3 | |
| Change, p=0.01 | -0.8±0.3 | -4.6±1.3 | |
| LV SW (cm2 × mmHg/m2) |
Pre-CPB | 215±24 | 360±111 |
| Post-CPB | 144±23 | 206±34 | |
| Change, p=0.34 | -70±8 | -154±95 | |
| EFa (%) |
Pre-CPB | 54±3 | 56±2 |
| Post-CPB | 42±4 | 40±6 | |
| Change, p=0.55 | -13±3 | -16±5 | |
| LVEDA at constant pressure (cm2/m2) |
Pre-CPB | 8.6±1.4 | 12.2±2.3 |
| Post-CPB | 6.6±0.9 | 8.7±2.2 | |
| Change, p=0.26 | -2.1±0.6 | -3.5±1.0 | |
| Am (cm2/m2) |
Pre-CPB | 10.9±1.5 | 10.0±2.1 |
| Post-CPB | 13.5±1.8 | 11.0±1.9 | |
| Change, p=0.28 | 2.6±1.0 | 1.1±0.5 |