Fig. 6.
Protective efficacy of KKF235 immunization against heterologous LVS challenge. BALB/c mice received a single immunizing dose (106 CFU) of KKF235 or PBS (mock control). Mice were rested for 30 days and then challenged i.n. with 3×104 CFU of LVS (∼10 LD50). Mice were then monitored for survival. Difference in survival between KKF235- and mock- vaccinated mice was significant at a p<0.001.