Table 1.

Age-, race-, and sex- adjusted baseline characteristics of controls according to quartiles of soluble endothelial protein C receptor (EPCR) levels: LITE.

	Quartiles of Soluble Endothelial Protein C Receptor (ng/ml)*
	65.4–121.7	121.9–139.8	140.1–169.5	170.4–1381	p for difference overall
No. of controls†	259	259	260	260
Age (years)†	59.7	61.8	64.3	63.5	<0.001
CHS (%)†	24	35	46	43	<0.001
White (%)†	62	79	75	77	<0.001
Men (%)†	33	47	46	48	<0.001
Body mass index	27.2	27.6	27.7	27.4	0.71
Diabetes (%)	11	8	13	14	0.15
Blood type non-O, %	46	55	50	59	0.02
Factor VIII (%)	124	126	131	131	0.16
Protein C (mg/L)‡	3.1	3.0	3.2	3.4	<0.001
F5 AA/AG genotype (%)	3	4	3	2	0.76
F2 AA/AG genotype (%)	3	2	2	1	0.31
PROCR AG/GG genotype (%)	0	1	1	66	<0.001

^*Quartiles based on the distribution in combined Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health Study (CHS) controls.

^†Unadjusted

^‡Protein C was available only for the ARIC subsample (n=642 for ARIC controls).