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. Author manuscript; available in PMC: 2009 Sep 28.
Published in final edited form as: Br J Haematol. 2009 Feb 17;145(2):221–226. doi: 10.1111/j.1365-2141.2009.07612.x

Table 1.

Age-, race-, and sex- adjusted baseline characteristics of controls according to quartiles of soluble endothelial protein C receptor (EPCR) levels: LITE.

Quartiles of Soluble Endothelial Protein C Receptor (ng/ml)*
65.4–121.7 121.9–139.8 140.1–169.5 170.4–1381 p for difference overall
No. of controls 259 259 260 260
Age (years) 59.7 61.8 64.3 63.5 <0.001
CHS (%) 24 35 46 43 <0.001
White (%) 62 79 75 77 <0.001
Men (%) 33 47 46 48 <0.001
Body mass index 27.2 27.6 27.7 27.4 0.71
Diabetes (%) 11 8 13 14 0.15
Blood type non-O, % 46 55 50 59 0.02
Factor VIII (%) 124 126 131 131 0.16
Protein C (mg/L) 3.1 3.0 3.2 3.4 <0.001
F5 AA/AG genotype (%) 3 4 3 2 0.76
F2 AA/AG genotype (%) 3 2 2 1 0.31
PROCR AG/GG genotype (%) 0 1 1 66 <0.001
*

Quartiles based on the distribution in combined Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health Study (CHS) controls.

Unadjusted

Protein C was available only for the ARIC subsample (n=642 for ARIC controls).