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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: J Card Fail. 2009 Apr;15(3):171–181. doi: 10.1016/j.cardfail.2009.01.013

Table 5.

Change in Heart Failure Medications On-Study by Patient

Cohort/Patient ID Change
Cohort 2/Pt# 1 β-blocker decreased at week 4
Cohort 2/Pt# 2 Diuretic increased on day 2
Cohort 2/Pt# 3 β-blocker decreased at week 6; diuretic decreased (week 7), increased (month 3) and then returned to baseline regimen (month 6)
Cohort 3/Pt# 1 Diuretic decreased at week 2; aldosterone antagonist decreased at week 4
Cohort 3/Pt# 2 Diuretic decreased at week 5 and again at week 6
Cohort 3/Pt# 3 Diuretics increased at week 2; other antihypertensive agent added at week 5; β-blocker decreased at week 3 and then increased to baseline dose over the weeks before early termination; angiotensin-converting enzyme inhibitor switched at week 4

The 3 patients in Cohort 1 had no changes in HF medications.