Table 5. Estimated effects (E) and Bonferroni corrected F-based p-values (p) for two-way ANOVA schemes applied to each immunological parameter separately, for each day of analysis.

	Day 31	Day 37	Day 52	Day59
PLV	a IL-4:	IFNγ:	IFNγ:	IFNγ:
	p = 0.026; E = 0.45	p = 0.001; E = 0.62	p = 0.05; E = 0.40	p = 0.02; E = 0.48
	IFNγ:
	p = 0.001; E = 0.62
FIVC	None	CD25:	IFNγ:	CD25:
		p = 0.0002; E = 0.70	p = 0.02; E = 0.47	p = 0.05; E = 0.40
		CD8:	FAS:	Neutr:
		p = 0.00005; E = 0.74	p = 0.02; E = 0.46	p = 0.0002; E = 0.70
		CD4:		IFNγ:
		p = 0.0005; E = 0.66		p = 0.001; E = 0.63
		Lymph:		FAS:
		p = 0.0005; E = 0.66		p = 0.03; E = 0.48
PLV × FIVC	None	None	None	None

Only significant effects are reported, with the name of the corresponding parameters.

^aThis value is not significant if ANOVA is run without imputing the values (p = 0.13).