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. 2009 Oct 7;4(10):e7360. doi: 10.1371/journal.pone.0007360

Figure 3. Dependence on KCl of contractile response to veratridine and TTX in the presence of prazosin.

Figure 3

The absence of endothelium was confirmed as described above. Representative recordings of isometric responses to veratridine (vera; 100 µmol/L) (A) or tetrodotoxin (TTX; 1 µmol/L) (B) after contraction induction by KCl (6 and 10 mmol/L) in the presence of 10 µmol/L prazosin (Pz). (C) Summary of results of the experiments described in A and B: the effects of veratridine (100 µmol/L) or TTX (1 µmol/L) on the contraction induced by KCl were expressed as a percentage of maximal contraction induced by PE (1 µmol/L). (D) Effects of TTX expressed as a percentage of KCl-induced contraction. Values represent the mean±s.e.m. of 6 animals, with experiments performed in duplicate. *p<0.05; **p<0.01; ***p<0.001, paired t-test.