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editorial
. 2003 Aug 15;89(Suppl 1):S4–S8. doi: 10.1038/sj.bjc.6601077

Table 1. The AGREE instrument.

Scope and purpose
1. The overall objective(s) of the guideline is (are) specifically described.
2. The clinical question(s) covered by the guideline is (are) specifically described
3. The patients to whom the guideline is meant to apply are specifically described
 
Stakeholder involvement
4. The guideline development group includes individuals from all the relevant professional groups
5. The patients' views and preferences have been sought
6. The target users of the guideline are clearly defined
7. The guideline has been piloted among target users
 
Rigour of development
8. Systematic methods were used to search for evidence
9. The criteria for selecting the evidence are clearly described
10. The methods for formulating the recommendations are clearly described
11. The health benefits, side effects and risks have been considered in formulating the recommendations
12. There is an explicit link between the recommendations and the supporting evidence
13. The guideline has been externally reviewed by experts prior to its publication
14. A procedure for updating the guideline is provided
 
Clarity and presentation
15. The recommendations are specific and unambiguous
16. The different options for management of the condition are clearly presented
17. Key recommendations are easily identifiable
18. The guideline is supported with tools for application
 
Applicability
19. The potential organisational barriers in applying the recommendations have been discussed
20. The potential cost implications of applying the recommendations have been considered
21. The guidelines present key review criteria for monitoring and/or audit purposes
 
Editorial independence
22. The guideline is editorially independent from the funding body
23. Conflicts of interest of guideline development members have been recorded