TABLE 4.
Tick bite infection of mice with B. burgdorferi lacking or containing GuaAB
| Clone | No. of mice infected by larval tick bite/total no. analyzeda | No. of mice infected by nymphal tick bite/total no. analyzeda | Total no. of mice infected/total no. analyzedb |
|---|---|---|---|
| A3-M9 guaA::flgBp-kan/pBSV2G | 0/4 | 0/4 | 0/8 |
| A3-M9 guaA::flgBp-kan/pBSV2G guaAB | 3/4 | 4/4 | 7/8 |
a
The data are pooled data from two separate tick feeding experiments. Infection was assessed by immunoblot analysis with cell lysates of B. burgdorferi and E. coli producing P39 recombinant protein at 3, 6, and 9 weeks postinoculation and by reisolation of spirochetes from ear, bladder, and joint tissues at 9 weeks postinoculation.
b
Based on total number of mice infected by larval and nymphal tick bites, the P value calculated by Fisher's exact test was 0.02.