TABLE 1.

Band 7 proteins of selected organisms used for the phylogenetic analysis shown in Fig. 1

Organism	Band 7 proteins (S/P/F/H/O)a	UniProt no.b	Proteins included in phylogenetic analysis
			NCBI no.	Protein name(s)	Annotationc
A. thaliana	7/11/0/0/4	O49460	NP_194580	Prohibitin 1/At4g28510	P
		O04331	NP_198893	Prohibitin 3/At5g40770	P
		Q9T082	NAd	At4g27580	S
		Q501E6e	NP_197907e	At5g25250	None
B. subtilis	0/0/1/0/0	O32076	NP_390979	YuaG	F
C. reinhardtii	1/2/0/0/1	A8I8V6	XP_001701753	Prohibitin 1	P
		A8J633	XP_001696940	Prohibitin 2	P
		A8JI52	XP_001703625	None	S
E. coli	1/0/0/2/1	P0AA53	NP_415022	YbbK/QmcA	S
		P0ABC3	NP_418596	HflC	H
		P0ABC7	NP_418595	HflK	H
		P77306	NP_417523	YqiK	None
G. violaceus	1/1/0/0/1	Q7NJI7	NP_924791	Gll1845	P
		Q7NIK9	NP_925120	Gll2174	S
		Q7NJI8	NP_924790	Gll1844	None
H. sapiensf	10/9/24/0/6	P35232	NP_002625	Prohibitin 1	P
		Q99623	NP_009204	Prohibitin 2	P
		P27105	NP_004090	Tomatin	S
			NP_937837
		O75955	NP_005794	Flotillin 1	F
		Q6FG43	NA	Flotillin 2	F
P. horikoshii	2/0/0/0/0	O59180	NP_143371	Stomatin/PH1511	S
S. cerevisiae	0/2/0/0/0	P40961	NP_011648	Prohibitin 1	P
		P50085	NP_011747	Prohibitin 2	P
Synechocystis sp. strain	1/1/0/0/3	P72754	NP_440089	Slr1106	P
PCC 6803		P73049	NP_440390	Slr1768	None
		P72655	NP_439977	Slr1128	S
		P74042	NP_441437	Sll0815	None
		P72929	NP_440266	Sll1021	None
T. elongatus	1/1/0/0/0	Q8DI32	NP_682550	Tlr1760	P
		Q8DGX8	NP_682974	Tlr2184	S

^aS, stomatins; P, prohibitins; F, flotillins; H, HflK/C; O, other proteins.

^bAccording to the UniProt database (version 14.6).

^cAnnotations as stomatin (S), prohibitin (P), flotillin (F), or HflK/C (H) are according to the InterPro database (release 18.0).

^dNA, not available.

^eQ501E6 of A. thaliana was included in this analysis because it has been identified in a detergent-resistant membrane fraction (4) and as a plant flotillin homologue (34).

^fSixteen of the 24 flotillins of H. sapiens listed in the InterPro database are fragments of flotillin-1.