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The fad regulon and the current model of its regulation by fatty acids. (A) Physical location of the fad regulon loci in the E. coli chromosome. The ybaW (fadM) gene is in bold font. (B) Repression of a fad gene in the absence of exogenous fatty acids. (C) Induction of fad gene upon the addition of exogenous fatty acids. The ovals represent FadR, whereas the circles denote the acyl-CoA regulatory ligand. FA, fatty acids.
