TABLE 5.

Genetic distances between HIV-1 viruses from LSC63 and P63^a

Gene or region	Pairwise nucleotide distance	P value	Synonymous distance	P value	Nonsynonymous distance	P value
gag	0.074	0.380	0.199	0.422	0.043	0.324
polA	0.061	0.338	0.163	0.570	0.035	0.127
polB	0.072	0.092	0.166	0.380	0.047	0.014
Central region	0.110	0.246
vif			0.196	0.042	0.065	0.662
vpr			0.168	0.788	0.067	0.451
vpu			0.225	0.317	0.121	0.261
gp120	0.152	0.120	0.207	0.282	0.136	0.099
gp41	0.126	0.035	0.199	0.239	0.105	0.021
nef	0.150	0.042	0.249	0.465	0.124	0.049

^aGenetic distances (per nucleotide) between the exposed viruses and the infecting viruses of LSC63 were calculated. The control group was comprised of 142 random subtype B whole-genome sequences. The P value is the percentage of random sequences whose distances to viruses of P63 were greater than the distance between the viruses of LSC63 and P63. P values of <0.05 are in bold font.