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. 2009 Sep 21;186(6):897–914. doi: 10.1083/jcb.200902096

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© 2009 Sumakovic et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 7. — In unc-108, NLP-21–YFP enters the late endosomal compartment. (A and B) To identify NLP-21–YFP-positive vesicular structures in wild type (A) and unc-108(n501) strains (B) carrying the NLP-21–YFP integrated array, different intracellular markers were expressed panneuronally: RAB-2, syn-6 (iDCVs), RAB-5 (early endosome), RAB-7 (late endosome), and LMP-1 (lysosome). The closed and open arrowheads represent larger and smaller vesicular structures, respectively. NLP-21–YFP-positive vesicles in the unc-108(n501) strain mostly colocalize with the early endosomal marker RAB-5. Bars, 2 µm.