Figure 6.
Membrane protrusions are abnormally shaped and disorganized in fiber cells lacking Tmod1. Cortical fiber peels from the anterior portion of 5-mo-old Tmod1+/+Tg+ (A and B) and of 8 mo-old Tmod1−/−Tg+ (C and D) mouse lenses, viewed from the inside looking out. Matched regions near the anterior suture depict en face views of the broad sides of overlapping fiber cells. B and D are higher magnification views from similar regions as in A and C. (B and D) Arrows indicate protrusions. Bars, 10 µm.