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. Author manuscript; available in PMC: 2009 Sep 28.
Published in final edited form as: Br J Dermatol. 2008 May 28;159(2):314–321. doi: 10.1111/j.1365-2133.2008.08624.x

Table 2. Interaction between the p53 Arg72Pro polymorphism and MC1R variants on childhood tanning tendency among controls.

p53\MC1R WT/WT WT/NRHC or NRHC/NRHC WT/RHC RHC/RHC or NRHC/RHC
Arg/Arg
 Tan/Non-tana 124/7 173/20 65/12 35/15
 Crude OR 1.00 0.49 (0.20-1.19) 0.31 (0.12-0.81) 0.13 (0.05-0.35)
 Multivariate ORb 1.00 0.45 (0.18-1.15) 0.36 (0.13-1.01) 0.26 (0.09-0.73)
Arg/Pro or Pro/Pro
 Tan/Non-tana 101/6 105/13 54/10 21/16
 Crude OR 0.95 (0.31-2.92) 0.46 (0.18-1.19) 0.31 (0.11-0.84) 0.07 (0.03-0.20)
 Multivariate ORb 0.68 (0.21-2.19) 0.45 (0.17-1.24) 0.28 (0.09-0.85) 0.14 (0.05-0.41)

WT stands for consensus allele. NRHC stands for non-red hair color allele. RHC stands for red hair color allele.

Four categories of the responses to the question of childhood tanning tendency were grouped into tan (light tan or average tan or tan) and non-tan (practically none).

a

The number of participants does not add up to the total women because of missing genotypes.

b

Unconditional logistic regression adjusted for natural skin color and natural hair color (p, interaction, 0.55).