Table 1.
Comparison of patient characteristics between study groups
|
Variables Baseline (preoperative) Data |
NSCC Group (n = 92) |
CABG Group (n = 220) |
p-value* |
|---|---|---|---|
| Gender | |||
| Male | 77.2% | 73.6% | |
| Female | 22.8% | 26.4% | |
| Non-white race | 6.5% | 9.1% | |
| Less than high school education | 16.3% | 20.9% | |
| On antidepressant | 13.0% | 11.0% | |
| History of past stroke or TIA | 5.4% | 9.5% | |
| History of hypertension | 50.0% | 65.5% | 0.008 |
| History of diabetes mellitus | 22.8% | 31.4% | |
| History of peripheral vascular disease | 6.6% | 20.0% | 0.002 |
| History of myocardial infarction | 48.9% | 49.1% | |
| History of angina | 60.9% | 79.1% | 0.001 |
| History of atrial fibrillation | 14.6% | 13.2% | |
| Family history of Alzheimer’s disease | 9.8% | 12.8% | |
| History of smoking | 55.4% | 70.0% | 0.01 |
| History of PTCA | 53.3% | 21.8% | 0.0001 |
| Apo-e4 present | 32.2% | 25.9% | |
| Mean age (years) | 65.9 (±9.2) | 64.6 (±9.8) | |
| Mean education (years) | 14.4 (±3.4) | 13.9 (±3.8) | |
| Mean # of disease coronary arteries | 1.95 (±0.8) | 2.66 (±0.6) | 0.0001 |
| Three vessel coronary disease | 26.8% | 72.0% | 0.0001 |
| Mean systolic blood pressure (mmHg) | 141 (±26) | 131 (±21) | 0.001 |
| Mean diastolic blood pressure(mmHg) | 79 (±13) | 72 (±11) | 0.0001 |
| Ave. mean arterial pressure (mmHg) | 100 (±16) | 92 (±13) | 0.0001 |
| Interim Follow-up Time Point Datac | |||
| 3 month | |||
| Died | 1/92 (1%) | 3/220 (1%) | |
| Refused/No contact | 7 (8%) | 47 (22%) | |
| Interviewed/tested | 84 (92%) | 170 (78%) | |
| Chest pain | 16 (19%) | 27 (16%) | |
| Myocardial infarction | 1 (1%) | 3 (2%) | |
| Redo cardiac angiogram | 2 (2%) | 6 (3%) | |
| PTCA | 1 (1%) | 2 (1%) | |
| 1 year | |||
| Died | 3/92 (3%) | 8/220 (4%) | |
| Refused/No contact | 5 (6%) | 32 (18%) | |
| Interviewed/tested | 84 (94%) | 174 (82%) | |
| Chest pain | 24 (29%) | 36 (21%) | |
| Myocardial infarction | 0 | 0 | |
| Redo cardiac angiogram | 4 (5%) | 8 (5%) | |
| PTCA | 1 (1%) | 3 (2%) | |
| 3 Year | |||
| Died | 6/92 (6%) | 20/220 (9%) | |
| Refused/No contact | 26 (30%) | 98 (49%) | |
| Interviewed/tested | 60 (70%) | 102 (51%) | |
| Chest pain | 22 (37%) | 24 (23%) | |
| Myocardial infarction | 1 (2%) | 2 (2%) | |
| Redo cardiac angiogram | 11 (18%) | 17 (17%) | |
| PTCA | 7 (12%) | 5 (5%) | |
| Had CABG surgery since last visit | 3 (5%) | 0 | |
| 6 Year | |||
| Died | 19/92 (21%) | 42/220 (19%) | |
| Refused/No contact | 12 (16%) | 42 (24%) | |
| Interviewed/tested | 61 (84%) | 136 (76%) | |
| Chest pain | 21 (34%) | 40 (29%) | |
| Myocardial infarction | 1 (2%) | 4 (3%) | |
| Redo cardiac angiogram | 13 (21%) | 24 (18%) | |
| PTCA | 5 (8%) | 10 (7%) | |
| Had CABG surgery since last visit | 7 (11%) | 0 |
*
only significant values shown;
c
not all patients were seen at each interim follow-up;
CABG – includes both on- and off-pump coronary artery bypass patients; NSCC – nonsurgical cardiac comparison; PTCA – percutaneous transluminal coronary angioplasty; TIA – transient ischemic attack