TABLE 2.
Mean metabolite concentrations of left and right hemisphere combined in 100% gray and white matter in controls and patients
| Region | Patients | Controls | % Difference |
|---|---|---|---|
| Frontal gray | |||
| NAA | 7.5 ± 0.91 | 8.1 ± 0.85 | 7.4a |
| Cr | 3.6 ± 0.32 | 3.4 ± 0.45 | 2.1 |
| Cho | 0.9 ± 0.16 | 0.8 ± 0.18 | 1.0 |
| Frontal white | |||
| NAA | 8.4 ± 0.96 | 8.9 ± 0.95 | 5.6 |
| Cr | 3.4 ± 0.41 | 3.4 ± 0.31 | 0 |
| Cho | 1.2 ± 0.19 | 1.2 ± 0.18 | 0 |
| Nonfrontal gray | |||
| NAA | 8.2 ± 0.91 | 8.3 ± 0.83 | 1.2 |
| Cr | 4.6 ± 0.59 | 4.7 ± 0.50 | 2.1 |
| Cho | 1.1 ± 0.23 | 1.1 ± 0.17 | 0 |
| Nonfrontal white | |||
| NAA | 8.6 ± 1.2 | 9.6 ± 1.1 | 10.4a |
| Cr | 3.3 ± 0.34 | 3.3 ± 0.42 | 0 |
| Cho | 1.1 ± 0.15 | 1.1 ± 0.22 | 0 |
NAA, N-acetyl aspartate; Cr, creatine/phosphocreatine; Cho, choline.
a
p < 0.05 when compared with controls with two-tailed signed-rank Wilcoxon test.