Table 3.

Average Annual Change in NEI-VFQ^a Scales Stratified by Clinical Indicators^b

Scale	Baseline Visual Acuity Worse than 20/40c		Baseline Corneal Curvature ≥52 Dd		Decline in Visual Acuity ≥10 Lettersc		Increase in Corneal Curvature ≥3.00 Dd		Incident Scar During 7-year Follow-up
	Yes (n = 33)	No (n = 892)	Yes (n = 280)	No (n = 645)	Yes (n = 170)	No (n = 749)	Yes (n = 115)	No (n = 809)	Yes (n = 149)	No (n = 775)
General vision	0.42	−0.08	−0.27	0.02	−0.938	0.125e	−0.980	0.066e	−0.694	0.058e
Ocular pain	1.40	0.18	0.40	0.15	−0.022	0.283	−0.389	0.320	−0.614	0.390e
Near activities	−0.46	−0.23	−0.21	−0.24	−0.888	−0.098e	−0.884	−0.148e	−0.640	−0.162
Distance activities	0.36	−0.04	−0.10	0.01	−0.885	0.160e	−0.840	0.087e	−0.655	0.092e
Social function	0.49	−0.19	−0.35	−0.08	−0.703	−0.067e	−0.432	−0.132	−0.412	−0.123
Mental health	0.21	0.49	0.68	0.39	−0.365	0.663e	−0.219	0.583e	−0.130	0.601e
Role difficulties	−0.24	−0.23	−0.58	−0.08	−0.976	−0.022e	−1.349	−0.074e	−1.064	−0.073e
Dependency	−1.09	−0.52	−1.03	−0.33e	−1.305	−0.365e	−1.952	−0.349e	−1.417	−0.381e
Driving	0.43	−0.13	−0.39	−0.01	−0.879	0.038e	−0.868	−0.014e	−0.610	−0.027e
Color vision	0.11	−0.20	−0.39	−0.10	−0.535	−0.121e	−0.070	−0.208	−0.644	−0.104e
Peripheral vision	0.77	−0.48	−0.72	−0.31	−1.129	−0.310e	−1.268	−0.320e	−0.702	−0.387

^aAnnual slope of change in NEI-VFQ scale score

^bA positive slope indicates improvement in reported quality of life, a negative slope indicates a decline.

^cEntrance High Contrast Binocular Vision

^dAverage of left and right eye

^eSignificant at p<0.05