Table 4.
The expression patterns of genes encoding brain and neural specific proteins during differentiation of ESC into serotonin neurons. The signal intensity on the microarray is reported. Robust and peak expressions are highlighted in red.
Brain & Neural Specific | |||||
---|---|---|---|---|---|
ESC | EB | N1 | N2 | N3 | |
ADAM10 | 2604 | 1324 | 1119 | 770 | 1067 |
PCDH1 | 341 | 72 | 68 | 80 | 10 |
PES1 | 449 | 266 | 252 | 100 | 239 |
CHRDL1 | 696 | 43 | 87 | 226 | 161 |
MDK | 3125 | 2205 | 2863 | 722 | 521 |
PCDHB9 | 1203 | 2342 | 3096 | 3903 | 3876 |
PCDH18 | 554 | 1265 | 2120 | 2751 | 1659 |
SLIT2 | 158 | 1440 | 2220 | 2080 | 2502 |
SEMA6D | 293 | 1107 | 951 | 1686 | 1395 |
SERPINI-1 | 134 | 424 | 458 | 419 | 597 |
PLXNA2 | 49 | 318 | 361 | 442 | 686 |
GAS7 | 107 | 549 | 1007 | 627 | 691 |
STMN2 | 372 | 791 | 5021 | 5577 | 9892 |
ROBO2 | 300 | 451 | 1269 | 2214 | 2431 |
PAFAH1B1 | 386 | 919 | 1198 | 1247 | 1373 |
NEGF1 | 516 | 232 | 1126 | 1591 | 3724 |
ROBO1 | 528 | 996 | 1134 | 2177 | 1698 |
DCX | 73 | 213 | 886 | 2585 | 4228 |
CRIM1 | 461 | 684 | 670 | 1585 | 1548 |
ENC1 | 772 | 857 | 995 | 1585 | 3058 |
WHSCI | 567 | 530 | 1044 | 903 | 1937 |
PALM | 686 | 1236 | 965 | 2390 | 2730 |
CHL1 | 42 | 27 | 310 | 1179 | 2701 |
NTRK2 | 94 | 294 | 775 | 1824 | 3540 |
OLFM1 | 501 | 506 | 684 | 1829 | 3482 |
NCAM1 | 172 | 463 | 918 | 2001 | 2933 |
NRXN1 | 421 | 149 | 282 | 842 | 1572 |
NRXN3 | 36 | 132 | 232 | 748 | 1102 |
CTNND2 | 105 | 250 | 256 | 582 | 767 |
INA | 1194 | 556 | 779 | 2615 | 5784 |
FEZ1 | 732 | 106 | 305 | 729 | 2418 |
CDKSR1 | 79 | 88 | 216 | 571 | 1246 |
GAP43 | 168 | 143 | 382 | 411 | 1378 |