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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2009 May;68(5):515–524. doi: 10.1097/NEN.0b013e3181a24b53

Figure 6.

Figure 6

High-power photomicrographs of human α-synuclein (LB509) immunostaining of nigral neurons in wild type (wt) (A–C), S129A (D–F), and S129D (G, H) recipients. Arrows indicate large intracytoplasmic 〈-synuclein-positive aggregates. Most aggregates were either perinuclear or in the periphery (A and G). B shows typical nuclear ghosting, consistent with neurodegenerative change. Dystrophic neurites in C have characteristic α-synuclein-positive inclusions (arrowheads). Bar: 5 ⌠m.