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Conceptual framework for an area co-endemic for S. mansoni and hookworm, where several rounds of mass drug administration take place. It highlights that treating all individuals in a co-endemic area with praziquantel and albendazole decreases the prevalence of S. mansoni and hookworm and consequently also the prevalence of co-infection. As a result, an ever growing proportion of individuals will be treated unnecessarily with one or even both drugs.
